Technologies of Yamasa
Our mission is to deliver high‑quality IVDs that advance the future of diagnosis and contribute to better medical care.
Delivering diagnostic precision to the future of medical care.
Yamasa leverages its two core strengths—antibody production technology and cell engineering technology—to develop IVDs with outstanding precision, reproducibility, and versatility. In particular, as the only manufacturer in Japan capable of providing bioassay products using cells as IVDs, we demonstrate a unique competitive advantage.
Cell-Based IVDs
Cell-based bioassays are powerful tools for evaluating the biological activity of target molecules. We utilize genetically engineered cells to provide unique IVDs capable of measuring biological activity with high precision.
Characteristics
- Measurement of biological activity: Enables measurement of cellular responses using the target molecule (real-time measurement is also possible).
- High reproducibility: Provides a stable detection system using transfected cells.
- Simple operation: Easy measurement process that only requires mixing the specimen with the cells.
- Applicable to a wide range of targets: Suitable for a broad range of targets, including various hormones and stimulatory/inhibitory autoantibodies.
Bioassay
Product Examples
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- IVD
- ENDOCRINE/METABOLISM
BIOSENSOR TSAb "YAMASA"
Measurement of thyroid-stimulating antibody :TSAb (diagnostic aid for Basedow's disease)
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- RESEARCH
BIOSENSOR TSBAb "YAMASA"
Measurement of TSH-stimulation blocking antibody:TSBAb
Antibodies-Based IVDs
Immunoassays that leverage the specificity of antibodies are ideal for detecting trace amounts of target molecules. With our proprietary antibody production technologies and optimized assay systems, we provide highly sensitive and highly selective immunoassay kits.
From designing and preparing antigens in-house—whether purified antigens derived from biological tissues or recombinant antigens—to immunizing animals and conducting screening using assay systems tailored to each application, we produce antibodies optimized for the intended diagnostic purpose.
Our immunoassay kits, which incorporate proprietary antibodies with exceptionally high affinity and selectivity for low–molecular weight antigens, are one of our distinguishing strengths.
Product Examples
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- IVD
- ENDOCRINE/METABOLISM
AVP KIT "YAMASA"
Measurement of Arginine Vasopressin (diagnostic aid for central diabetes insipidus)
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- IVD
- ENDOCRINE/METABOLISM
Renin Activity KIT "YAMASA"
Measurement of Renin Activity (diagnostic aid for secondary hypertension such as primary aldosteronism)
Immunoassay schematic
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Uses a primary antibody, which binds to the target antigen (or an antigen in a sample), and a secondary antibody, which specifically binds to the primary antibody, to detect the antigen. The secondary antibody helps amplify the signal, thereby improving sensitivity.
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Based on the principle that labeled antigens and antigens in the sample compete for antibody binding sites. It allows highly quantitative measurement through signal changes corresponding to concentration, even for low-molecular-weight antigens.
